Absence of 185delAG and 6174delT Mutations among Breast Cancer Patients of Eastern India
نویسندگان
چکیده
منابع مشابه
Molecular Analysis of 185delAG and 6174delT Mutations in Eastern Indian Breast Cancer Cases
Breast cancer (BC) is a form of cancer in the glandular breast tissue. In India, women diagnosed with carcinoma of the breast is on an average of 80,000 and women die of this disease every year is 40,000, and it is marked as the second most common cancer among Indian women (19%) after cervical cancer (30%) (Saxena et al. 2006). For the development of breast and ovarian cancers there may be seve...
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A recent report estimated the breast cancer risks in carriers of the three Ashkenazi founder mutations to be higher than previously published estimates derived from population based studies. In an attempt to confirm this, the breast and ovarian cancer risks associated with the three Ashkenazi founder mutations were estimated using families included in a previous meta-analysis of populatrion bas...
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Germline mutations in the BRCA1 or BRCA2 genes predispose their carriers to breast or/and ovary cancers during their lifetime. The most frequent mutations: 5382insC, 185delAG, C61G and 4153delA in BRCA1, and 6174delT and 9631delC in BRCA2 were studied in a group of 148 probands admitted for genetic counseling, using allele-specific amplification (ASA) PCR test. Fifteen carriers of three differe...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2015
ISSN: 1513-7368
DOI: 10.7314/apjcp.2015.16.17.7929